apa arti maco
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MACO Calculation Using PDE. MACO = (PDE × MBS) / MDD. Where, MACO: Maximum allowable carry over in mg; PDE: Permitted daily exposure of the previous product; MBS: Minimum batch size for the next product in mg; MDD: Maximum Daily dose of the next product in mg ; MACO Calculation Using LD50 and NOEL mecobalamin 500mg obat apa
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